First report on sexually transmitted infections among trans (male to female transvestites, transsexuals, or transgender) and male sex workers in Argentina: high HIV, HPV, HBV, and syphilis prevalence
First report on sexually transmitted infections among trans (male to female transvestites, transsexuals, or transgender) and male sex workers in Argentina: high HIV, HPV, HBV, and syphilis prevalence
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DOI：
10.1016/j.ijid.2011.05.007
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发表时间：
2011-09-01
影响因子：
8.4
通讯作者：
Mercedes Avila, Maria
中科院分区：
文献类型：
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作者：
dos Ramos Farias, Maria Sol;Noe Garcia, Maria;Mercedes Avila, Maria
目的：由于阿根廷男女变性工作者（TSW）和男性性工作者（MSW）中性传播感染（STI）流行率的数据稀缺，本研究旨在估计人类免疫缺陷病毒（HIV）的发病率，以及艾滋病毒、乙型肝炎病毒（HBV）、丙型肝炎病毒（HCV）和梅毒螺旋体的流行率。对 TSW 进行了人乳头瘤病毒（HPV）和沙眼衣原体感染检测。方法：由非政府组织招募了 273 名 TSW 和 114 名 MSW。 HIV 发病率通过 STARHS（近期 HIV 血清转化的血清学检测算法）进行估计。在 TSW 的肛门细胞中测试了 HPV 和沙眼衣原体感染。结果：与 MSW 相比，TSW 的 HIV（34.1 vs. 11.4%）、HBV（40.2 vs. 22.0%）和梅毒螺旋体（50.4 vs. 20.4%）的患病率显着更高。 TSW 在 111/114 例中检测出 HPV 阳性，在 4/80 例中检测出沙眼衣原体呈阳性。对 HBV、HCV、HIV 和梅毒螺旋体混合感染的调查显示，72% 的 TSW 和 39% 的 MSW 至少患有一种性传播感染。梅毒螺旋体是最常见的单一感染。 TSW 的艾滋病毒发病率估计为每 100 人年 10.7 例（95% 置信区间 (CI) 3.8-17.7），MSW 的艾滋病毒发病率估计为每 100 人年 2.3 例（95% CI 0-6.7）。 结论：性传播感染的高患病率和艾滋病毒的高发病率表明这些高危人群的脆弱性，并表明迫切需要采取干预措施和促进获得医疗保健的预防策略程序。 (C) 2011 年国际传染病学会。由爱思唯尔有限公司出版。保留所有权利。
Objectives: Due to the scarce data on the prevalence of sexually transmitted infections (STIs) among male-to-female trans-sex workers (TSW) and male sex workers (MSW) in Argentina, the present study aimed to estimate the incidence of human immunodeficiency virus (HIV), and the prevalence of HIV, hepatitis B virus (HBV), hepatitis C virus (HCV), and Treponema pallidum. Human papillomavirus (HPV) and Chlamydia trachomatis infections were tested among TSW.Methods: Two hundred and seventy-three TSW and 114 MSW were recruited by nongovernmental organizations. HIV incidence was estimated by STARHS (serologic testing algorithm for recent HIV seroconversion). HPV and C. trachomatis infections were tested in anal cells from TSW.Results: TSW showed significantly higher prevalences of HIV (34.1 vs. 11.4%), HBV (40.2 vs. 22.0%), and T. pallidum (50.4 vs. 20.4%) than MSW. TSW tested positive for HPV in 111/114 cases and for C. trachomatis in 4/80 cases. Investigation of HBV, HCV, HIV, and T. pallidum co-infections showed that 72% of TSW and 39% of MSW had at least one STI. T. pallidum was the most frequent mono-infection. The estimated HIV incidence was 10.7 per 100 person-years (95% confidence interval (CI) 3.8-17.7) for TSW and 2.3 per 100 person-years (95% CI 0-6.7) for MSW.Conclusions: The high prevalence of STIs and the high incidence of HIV demonstrate the great vulnerability of these high-risk populations and indicate the urgent need for preventive strategies on intervention and facilitation of access to healthcare programs. (C) 2011 International Society for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.