National Trends in Suicide Thoughts and Behavior among US Adults with Opioid Use Disorder from 2015 to 2020.

National Trends in Suicide Thoughts and Behavior among US Adults with Opioid Use Disorder from 2015 to 2020.
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DOI:
10.1080/10826084.2022.2046102
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发表时间:
2022
影响因子:
2
通讯作者:
Weinberger, Andrea H.
Weinberger, Andrea H.
中科院分区:
医学4区
文献类型:
--
作者:
Streck, Joanna M.;Parker, Maria A.;Bearnot, Benjamin;Kalagher, Kelly;Sigmon, Stacey C.;Goodwin, Renee D.;Weinberger, Andrea H.

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自杀想法和行为(STB)与过早死亡有关,并且在阿片类药物使用障碍(OUD)患者中不成比例。缺乏OUD患者中STB的最新趋势。我们使用六波具有全国代表性的横截面流行病学数据,调查了有OUD和无OUD的美国成年人中STB的趋势。数据来自2015-2020年全国药物使用和健康调查(合并n= 241,675)。我们比较了过去一年的STB结果(即,在有与没有过去一年OUD的成年人中,认真考虑自杀(SI),自杀计划(SP),自杀企图(SA)的想法。未经调整和调整的逻辑回归测试了调查年和去年STB结果之间的关联(即,SI、SP/SA)。在2015-2020年期间,分别有26%和4%的OUD患者报告了SI,10%和1%报告了SP,6%和1%报告了SA(所有ps<0.001)。在校正分析中,在调查年份中,未观察到有或无OUD的成人SI患病率的变化,也未观察到有或无OUD的成人SP/SA随时间的变化。OUD的严重程度和治疗状态并没有调节OUD和STB结果之间的关系。在美国成年人中,OUD与自杀想法和自杀行为有关。近年来,成人OUD患者中STB的患病率升高并没有改变。在报告阿片类药物滥用的人群中需要筛查SI,并应常规纳入OUD预防和治疗。
Suicide thoughts and behavior (STB) are associated with premature mortality and is disproportionately represented among those with opioid use disorder (OUD). Recent trends in STB among those with OUD are lacking. We investigated trends in STB among US adults with versus without OUD using six waves of cross-sectional, nationally-representative, epidemiological data. Data came from the 2015-2020 National Survey on Drug Use and Health (combined n=241,675). We compared past-year STB outcomes (i.e., thoughts of seriously considering killing self (SI), suicide plan (SP), suicide attempt (SA)) among adults with versus without past-year OUD. Unadjusted and adjusted logistic regression tested the association between survey-year and past-year STB outcomes (i.e., SI, SP/SA) stratified by OUD status. Between 2015-2020, 26% versus 4% of those with and without OUD, respectively, reported SI, 10% versus 1% reported a SP, and 6% versus 1% reported SA (all ps<0.001). In adjusted analyses, across survey years, no changes in the prevalence of SI were observed for adults with or without OUD, and no changes were observed over time for SP/SA in adults with or without OUD. OUD severity and treatment status did not moderate the relationship between OUD and STB outcomes. Among US adults, OUD was associated with thoughts of suicide and suicide behavior. The heightened prevalence of STB in adults with OUD has not changed in recent years. Screening for SI is needed among those reporting opioid misuse and should be routinely integrated into OUD prevention and treatment.
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