N,N-dimethyl-D-glucosamine as an efficient ligand for coppercatalyzed Ullmann-type coupling of N-H heterocycles with aryl halides
N,N-dimethyl-D-glucosamine as an efficient ligand for coppercatalyzed Ullmann-type coupling of N-H heterocycles with aryl halides
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N,N-二甲基-D-葡萄糖胺作为铜催化 N-H 杂环与芳基卤的乌尔曼型偶联的有效配体
DOI：
10.1016/j.tet.2017.11.027
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发表时间：
2017
期刊：
影响因子：
2.1
通讯作者：
Li Jiang Xuan
中科院分区：
文献类型：
--
作者：
Jiao Jiao Wei;Wei Bin Song;Ye Fu Zhu;Bo Le Wei;Li Jiang Xuan
已经开发了一种新的N，N-二甲基-D-葡糖胺配体用于铜催化的N-H杂环（例如，吲哚类、苯并咪唑类、吡唑类和三唑类）与芳基卤化物的反应。该方法不仅具有产率高、反应条件温和、操作简便等优点，而且具有环境友好、底物广谱等特点，可广泛应用于N-芳基杂环体系的the.construction。
A new N,N-dimethyl-D-glucosamine ligand has been developed for the copper-catalyzed Ullmann-type.coupling of N-H heterocycles (e.g., indoles, benzimidazoles, pyrazoles and triazoles) with aryl halides..This method was accomplished not only featuring excellent yields, mild reaction conditions and simple.operation, but also showing eco-friendly and broad-spectrum substrates, and could be widely used in the.construction of N-aryl heterocyclic systems.