GENETICS OF SIGNAL-TRANSDUCTION IN INVERTEBRATES
GENETICS OF SIGNAL-TRANSDUCTION IN INVERTEBRATES
复制标题
DOI：
10.1016/0959-437x(94)90092-2
复制
发表时间：
1994-02-01
影响因子：
4
通讯作者：
HAFEN, E
中科院分区：
文献类型：
--
作者：
DICKSON, B;HAFEN, E
受体酪氨酸激酶在无脊椎动物发育过程中调节许多不同的细胞命运决定。由这些激酶激活的信号转导通路的遗传分析表明，它们会聚在一个共同的途径，涉及Ras和级联的细胞质激酶，在细胞核中再次发散与特定的转录因子的调节。
Receptor tyrosine kinases regulate a number of different cell fate decisions during invertebrate development. Genetic analysis of the signal transduction pathways activated by these kinases suggests that they converge upon a common pathway involving Ras and a cascade of cytoplasmic kinases, diverging again in the nucleus with the regulation of specific transcription factors.