Miniaturized crossflow ion transfer device for post-column enrichment in ion chromatography
Miniaturized crossflow ion transfer device for post-column enrichment in ion chromatography
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DOI：
10.1016/j.talanta.2020.120989
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发表时间：
2020-08-15
期刊：
影响因子：
6.1
通讯作者：
Toda, Kei
中科院分区：
文献类型：
--
作者：
Ohira, Shin-Ichi;Sakaki, Tomomi;Toda, Kei
采用电渗析柱后富集提高了离子色谱系统的灵敏度。尽管柱后反应，如抑制，已被用于提高灵敏度，只有少数方法可用于增加浓度和提高灵敏度。柱后在线富集实现了小型化的错流离子转移装置（ITD）在我们的实验室制备。在错流ITD中，抑制洗脱液中分离的离子溶质被转移到受体溶液（在线纯化超纯水）中，其流速小于洗脱液的流速。由于高效的离子转移，分析物在受体溶液中富集，富集因子取决于受体与洗脱剂的流速比。此外，横流ITD最小化了通道中的峰值分散。当流速比为10时，检测限提高了5.0 ± 0.3倍。
The sensitivity of an ion chromatography system was improved using electrodialytic post-column enrichment. Even though post-column reactions, such as suppression, have been used to enhance the sensitivity, there are only a few methods available to increase the concentration and improve the sensitivity. Post-column in-line enrichment was achieved with a miniaturized crossflow ion transfer device (ITD) prepared in our laboratory. In the crossflow ITD, separated ionic solutes in the suppressed eluent were transferred into the acceptor solution (in-line purified ultrapure water), which had a flow rate less than that of the eluent. Because of highly efficient ion transfer, the analytes were enriched in the acceptor solution and the enrichment factor was depending on flow rate ratio of acceptor to eluent. Furthermore, the crossflow ITD minimized peak dispersion in the channel. The limit of detection improved by 5.0 +/- 0.3 times when the flow rate ratio was 10.