NEUROENDOCRINE, PSYCHOPHYSIOLOGICAL AND SUBJECTIVE REACTIVITY TO AN ALCOHOL PLACEBO IN MALE ALCOHOLIC PATIENTS
NEUROENDOCRINE, PSYCHOPHYSIOLOGICAL AND SUBJECTIVE REACTIVITY TO AN ALCOHOL PLACEBO IN MALE ALCOHOLIC PATIENTS
复制标题
DOI：
10.1111/j.1530-0277.1987.tb01311.x
复制
发表时间：
1987-06-01
期刊：
影响因子：
--
通讯作者：
POMERLEAU, OF
中科院分区：
文献类型：
--
作者：
DOLINSKY, ZS;MORSE, DE;POMERLEAU, OF
与能量代谢和食物摄入调节相关的神经内分泌活动的改变可能在表征酒精依赖状态中发挥作用。与对照组相比，酗酒者在饮用安慰剂啤酒（他们认为含有酒精）后，表现出更大、更快的葡萄糖和胰岛素反应。在酗酒者中，神经内分泌峰值反应与饮酒欲望、焦虑以及心理生理反应之间存在显著相关性，这表明与酒精依赖相关的生物/行为状态具有潜在的多变量性质。
Alteration in neuroendocrine activity associated with the regulation of energy metabolism and food intake may play a role in characterizing the alcohol dependent state. Alcoholics, when compared to controls, demonstrated significantly larger and more rapid glucose and insulin responses following the consumption of a placebo beer, which they believed contained alcohol. The existence of significant correlations between peak neuroendocrine responses and desire to drink, anxiety, as well as psychophysiological responses in alcoholics suggests the potential multivariate nature of the biological/behavioral state associated with alcohol dependence.