DELINEATION OF PANCREAS WITH MR-IMAGING - MULTIOBSERVER COMPARISON OF 5 PULSE SEQUENCES
DELINEATION OF PANCREAS WITH MR-IMAGING - MULTIOBSERVER COMPARISON OF 5 PULSE SEQUENCES
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DOI：
10.1002/jmri.1880050215
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发表时间：
1995-03-01
期刊：
影响因子：
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通讯作者：
EHRLICH, SM
中科院分区：
文献类型：
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作者：
MITCHELL, DG;WINSTON, CB;EHRLICH, SM
作者比较了五种磁共振（MR）成像脉冲序列对59名患者胰腺的描绘能力，每种序列至少用五种序列中的两种进行评估。8例患者存在局灶性胰腺癌。5个序列分别为t1加权自旋回波（T1-SE）、脂肪抑制TP-SE （T1-FS）、t1加权梯度回波（T1-GRE）、t2加权SE （T1-SE）和t2加权快速自旋回波（T2-FSE）。使用重复测量分析，三名盲法观察者独立地回顾了198个单独的MR成像系列，并根据图像质量、胰腺边界的描绘以及包含胰腺和胆总管的切片数量，以5分制对它们进行评分。记录每位患者每个序列中包含胰腺的最上、最下切片。用方差分析比较结果，用类内相关系数（intraclass correlation coefficient， ICC）衡量观察者间一致性。对于图像质量，所有序列都被评为良好到优秀，其中T1-SE序列的评分最高。然而，对于胰腺边界的清晰度，T1-FS序列的评分明显高于其他序列（P < 0.006）；T2-SE序列最不令人满意。T2-FSE序列的大部分切片可见总胆管和胰管。在大多数含有胰腺的上下切片的识别上没有显著差异，所有序列的PCC都很高（0.91 - 0.97）。对于局灶性癌的检测，单一脉冲序列是不够的。
The authors compared five magnetic resonance (MR) imaging pulse sequences for their ability to depict the pancreas in 59 patients, each evaluated with at least two of the five sequences. Focal pancreatic carcinomas were present in eight patients. The five sequences were T1-weighted spin echo (T1-SE), fat-suppressed TP-SE (T1-FS), T1-weighted gradient echo (T1-GRE), T2-weighted SE (T1-SE), and T2-weighted fast spin echo (T2-FSE). Using repeated-measures analysis, three blinded observers independently reviewed 198 separate MR imaging series and rated them on a 5-point scale with regard to image quality and depiction of pancreatic borders and the number of sections containing pancreatic and common bile ducts. The most superior and most inferior sections containing pancreas were recorded for each sequence in each patient. The results were compared with analysis of variance, and interobserver agreement was measured with the intraclass correlation coefficient (ICC). For image quality, all sequences were rated good to excellent, with the T1-SE sequence having the highest rating. For clarity of pancreatic borders, however, the T1-FS sequence was rated significantly higher (P < .006) than the other sequences; the T2-SE sequence was least satisfactory. Common bile and pancreatic ducts were seen in the most sections with the T2-FSE sequence. There were no significant differences regarding identification of the most superior and inferior sections containing pancreas, and the PCC was high (.91-.97) for all sequences. For detecting focal carcinomas, no single pulse sequence was sufficient.