Classification of abused inhalants

Classification of abused inhalants
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DOI:
10.1111/j.1360-0443.2008.02494.x
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发表时间:
2009-06-01
期刊:
影响因子:
6
通讯作者:
Cottler, Linda B.
Cottler, Linda B.
中科院分区:
医学1区
文献类型:
--
作者:
Balster, Robert L.;Cruz, Silvia L.;Cottler, Linda B.

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数以百计的家庭和工业产品很容易挥发,容易被滥用。吸入剂滥用研究一直受到以下问题的阻碍:对于是否根据产品的化学结构、形式或预期用途或药理特性对滥用吸入剂进行细分,缺乏共识。本文讨论了吸入剂分类的各种方法的优缺点,并提出了今后在这一领域的研究领域。结论是,按形式或产品类型对吸入剂进行分类对科学目的没有用处;相反,对吸入剂的细分分类应以尚未确定的化学和药理相似性以及共同滥用模式的组合为基础。我们能够更好地了解吸入剂滥用的方法之一是获得关于个别产品和化学品、其使用模式和其使用的地理分布的更详细的信息。
Many hundreds of household and industrial products can be volatilized readily and are subject to abuse. Inhalant abuse research has been hampered by a lack of consensus on whether or not there are subclassifications of abused inhalants based on chemical structure, form or intended use of the product or pharmacological properties. This paper discusses strengths and weaknesses of various approaches to classification of inhalants and suggests areas for future research in this area. It is concluded that classification of inhalants by form or product types is not useful for scientific purposes; rather, subclassification of inhalants should be based on a yet-to-be-determined combination of chemical and pharmacological similarity and shared patterns of abuse. One of the ways in which we can improve our understanding of inhalant abuse is to obtain more detailed information on individual products and chemicals, their patterns of use and the geographical distribution of their use.