Cross-sex genetic correlations for fitness and fitness components: Connecting theoretical predictions to empirical patterns
Cross-sex genetic correlations for fitness and fitness components: Connecting theoretical predictions to empirical patterns
复制标题
DOI：
10.1002/evl3.116
复制
发表时间：
2019-06-01
影响因子：
5
通讯作者：
Matthews, Genevieve
中科院分区：
文献类型：
--
作者：
Connallon, Tim;Matthews, Genevieve
在形态、生理、发育和行为上的性别差异是普遍存在的，但两性遗传了几乎相同的基因组，导致大多数性状表现出强烈的正向跨性别遗传相关性。与大多数其他性状相反，适合度和适合度分量（r（W）（fm））的跨性别遗传相关性的估计通常较低，偶尔为负，这意味着适合度的大部分常设遗传变异可能是性拮抗的（即，对一种性别有利的等位基因对另一种性别有害）。然而，虽然r（W）（fm）的低值通常被认为是性拮抗选择的结果，但仍不清楚数量性状的选择和变异如何相互作用以确定r（W）（fm）的符号和大小，因此很难将跨性别遗传相关性的经验估计与可能塑造它们的进化过程联系起来。我们提出了简单的单变量和多变量的定量遗传模型，明确的性别特异性选择和性状遗传变异的跨性别的遗传相关健身模式。我们表明，r（W）（调频）提供了一个不可靠的信号，性拮抗选择有两个原因。首先，r（W）（fm）被限制为小于影响适合度的性状的跨性别遗传相关，而不管性状选择的性质如何。第二，性拮抗选择是一个不充分的条件，产生负面的跨性别遗传相关的健身。相反，两性之间的负健身相关（r（W）（fm））
Sex differences in morphology, physiology, development, and behavior are widespread, yet the sexes inherit nearly identical genomes, causing most traits to exhibit strong and positive cross-sex genetic correlations. In contrast to most other traits, estimates of cross-sex genetic correlations for fitness and fitness components (r(W)(fm) ) are generally low and occasionally negative, implying that a substantial fraction of standing genetic variation for fitness might be sexually antagonistic (i.e., alleles benefitting one sex harm the other). Nevertheless, while low values of r(W)(fm) are often regarded as consequences of sexually antagonistic selection, it remains unclear exactly how selection and variation in quantitative traits interact to determine the sign and magnitude of r(W)(fm) , making it difficult to relate empirical estimates of cross-sex genetic correlations to the evolutionary processes that might shape them. We present simple univariate and multivariate quantitative genetic models that explicitly link patterns of sex-specific selection and trait genetic variation to the cross-sex genetic correlation for fitness. We show that r(W)(fm) provides an unreliable signal of sexually antagonistic selection for two reasons. First, r(W)(fm) is constrained to be less than the cross-sex genetic correlation for traits affecting fitness, regardless of the nature of selection on the traits. Second, sexually antagonistic selection is an insufficient condition for generating negative cross-sex genetic correlations for fitness. Instead, negative fitness correlations between the sexes (r(W)(fm)