What Black Women Know and Want to Know About Counseling and Testing for BRCA1/2.
What Black Women Know and Want to Know About Counseling and Testing for BRCA1/2.
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黑人妇女知道并想了解BRCA1/2的咨询和测试。
DOI：
10.1007/s13187-014-0740-9
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发表时间：
2015-06
期刊：
影响因子：
--
通讯作者：
Sheppard VB
中科院分区：
文献类型：
--
作者：
Adams I;Christopher J;Williams KP;Sheppard VB
黑人妇女与白色妇女一样可能有遗传性乳腺癌突变，但他们参与遗传咨询和检测的程度要低得多。本研究旨在描述黑人妇女的认识和BRCA 1/2测试的看法，并确定障碍和动机，寻求BRCA 1/2服务。在华盛顿的公共场所（职业女子篮球比赛、杂货店、信仰社区活动和乳房护理诊所的等候区），对50名黑人妇女进行了拦截采访。超过一半的女性（54%）知道存在基因检测来确定某些乳腺癌和卵巢癌的风险，但大多数（88%）从未听说过BRCA 1/2。在听到BRCA 1/2遗传标记的描述后，82%的人表示，如果向他们提供BRCA 1/2检测，他们会同意。人们认为检测的优势包括预防癌症和与家人分享信息的能力。被认为的缺点包括与突变识别相关的情绪困扰，以及可能滥用结果来拒绝医疗保健或就业。医生的建议，自我保健，和已知的家族史是测试的动机。妇女列举了可能的干预媒体和渠道。尽管黑人社区的BRCA 1/2检测率较低，但该样本中的妇女对这一想法持开放态度。有必要采取干预措施，消除障碍，包括文化调整。
Black women are just as likely to have hereditary breast cancer mutations as White women, yet their participation in genetic counseling and testing is substantially lower. This study sought to describe Black women’s awareness and perceptions of BRCA1/2 testing and to identify barriers and motivators to seeking BRCA1/2 services. Fifty intercept interviews were conducted with Black women in public places (a professional women’s basketball game, a grocery store, a faith-based community event, and the waiting area at a breast care clinic) in Washington, DC. More than half of the women (54%) were aware that genetic tests to determine risk for certain breast and ovarian cancers exist, but the majority (88%) had never heard of BRCA1/2 , specifically. After hearing a description of BRCA1/2 genetic markers, 82% stated that they would agree to BRCA1/2 testing if it was offered to them. Perceived advantages of testing included cancer prevention and the ability to share information with family members. Perceived disadvantages included emotional distress associated with identification of the mutation and the potential misuse of results to deny healthcare or employment. Physician recommendation, self-care, and known family history were among the motivators for testing. Women listed possible media and venues for intervention. In spite of low rates of BRCA1/2 testing in the Black community, women in this sample were open to the idea. Interventions that address barriers and include cultural tailoring are necessary.
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DOI：
10.1089/10906570260199366
发表时间：
2002-06-01
期刊：
GENETIC TESTING
影响因子：
--
作者：
Armstrong, K;Stopfer, J;Weber, B
通讯作者：
Weber, B
影响因子：
1.9
作者：
Hall, Michael J;Dignam, James J;Olopade, Olufunmilayo I
通讯作者：
Olopade, Olufunmilayo I
影响因子：
2.8
作者：
Gullatte, Mary Magee;Brawley, Otis;Mooney, Kathi
通讯作者：
Mooney, Kathi
影响因子：
3.7
作者：
Greenup, Rachel;Buchanan, Adam;Hwang, E. Shelley
通讯作者：
Hwang, E. Shelley
影响因子：
0.7
作者：
Cutilli, Carolyn Crane
通讯作者：
Cutilli, Carolyn Crane