Contribution of the Na(+)-K+ pump to membrane potential in familial periodic paralysis.

Contribution of the Na(+)-K+ pump to membrane potential in familial periodic paralysis.
复制标题

Na( )-K 泵对家族性周期性麻痹中膜电位的贡献。

DOI:
10.1002/mus.880080503
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发表时间:
1985
期刊:
影响因子:
3.4
通讯作者:
Levinson,SR
Levinson,SR
中科院分区:
医学3区
文献类型:
--
作者:
Martin,AR;Levinson,SR

文献摘要

相似文献

The possibility has been raised that in familial periodic paralysis, the relatively large depolarization of the muscle fiber membrane seen during periods of paralysis might be attributable to a reduction in activity of the electrogenic Na+‐K+pump. The theoretical analysis presented here shows that although such hypotheses are qualitatively correct, the quantitative contribution of the electrogenic pump is too small to account entirely for the changes in membrane potential observed between the paralytic and interictal states.