Radical-scavenging activity of natural methoxyphenols vs. synthetic ones using the induction period method
Radical-scavenging activity of natural methoxyphenols vs. synthetic ones using the induction period method
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DOI：
10.3390/12020130
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发表时间：
2007-02-01
期刊：
影响因子：
4.6
通讯作者：
Fujisawa, Seiichiro
中科院分区：
文献类型：
--
作者：
Kadoma, Yoshinori;Atsumi, Toshiko;Fujisawa, Seiichiro
合成抗氧化剂2-烯丙基-4-X-苯酚的自由基清除活性（X=NO2，Cl，Br，OCH 3，COCH 3，CH 3，t-（CH 3）（3），C6 H5）和2，4-二甲氧基苯酚，以及天然抗氧化剂丁香酚和异丁香酚的抗1，研究了偶氮二异丁腈（AIBN）和过氧化苯甲酰（BPO）热分解引发甲基丙烯酸甲酯（MMA）聚合的DPPH自由基活性和诱导期。与丁香酚和异丁香酚相比，2-烯丙基-4-甲氧基苯酚和2，4-二甲氧基苯酚不仅能更有效地清除来自BPO的氧中心自由基（PhCOO），而且能更有效地清除来自AIBN和DPPH自由基的碳中心自由基（R）。2-烯丙基-4-甲氧基苯酚可能因其较低的促氧化活性而有用。
The radical-scavenging activities of the synthetic antioxidants 2-allyl-4-X-phenol (X=NO2, Cl, Br, OCH3, COCH3, CH3, t-(CH3)(3), C6H5) and 2,4-dimethoxyphenol, and the natural antioxidants eugenol and isoeugenol, were investigated using differential scanning calorimetry (DSC) by measuring their anti-1,1-diphenyl-2-picrylhydrazyl (DPPH) radical activity and the induction period for polymerization of methyl methacrylate (MMA) initiated by thermal decomposition of 2,2'-azobisisobutyronitrile (AIBN) and benzoyl peroxide (BPO). 2-Allyl-4-methoxyphenol and 2,4-dimethoxyphenol scavenged not only oxygen-centered radicals (PhCOO) derived from BPO, but also carbon-centered radicals (R) derived from the AIBN and DPPH radical much more efficiently, in comparison with eugenol and isoeugenol. 2-Allyl-4-methoxyphenol may be useful for its lower prooxidative activity.