Two‐Photon Polymerized Shape Memory Microfibers: A New Mechanical Characterization Method in Liquid
Two‐Photon Polymerized Shape Memory Microfibers: A New Mechanical Characterization Method in Liquid
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DOI：
10.1002/adfm.202206739
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发表时间：
2022-09
影响因子：
19
通讯作者：
Grayson Minnick;Bahareh Tajvidi Safa;J. Rosenbohm;N. Lavrik;Justin R. Brooks;A. M. Esfahani;Alberto Samaniego;Fanben Meng;Benjamin Richter;Wei Gao;Ruiguo Yang
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文献类型：
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作者：
Grayson Minnick;Bahareh Tajvidi Safa;J. Rosenbohm;N. Lavrik;Justin R. Brooks;A. M. Esfahani;Alberto Samaniego;Fanben Meng;Benjamin Richter;Wei Gao;Ruiguo Yang
双光子聚合（TPP）被广泛用于创建生物学和机械生物学研究的3D微米和纳米级支架，这通常需要对TPP制造的结构进行机械表征。为了满足生理要求，大多数力学表征需要在液体中进行。然而，由于传统的微米和纳米级机械测试方法的限制，以前对TPP制造结构的表征都是在空气中进行的。在这项研究中，报告了一种新的实验方法，用于测试TPP打印微纤维在液体中的机械性能。实验结果表明，超细纤维在液体中的力学性能与在空气中的力学性能有很大的不同。通过控制TPP写入参数，可以在宽范围内定制微纤维的机械性能，以满足各种机械生物学应用。此外，还发现，在水中，塑性变形的微纤维可以恢复到其预变形后的形状后，拉伸应变释放。形状恢复时间取决于微纤维的尺寸。该实验方法代表了TPP制造结构的机械测试的重大进步，并可能有助于释放TPP制造的3D组织支架的机械生物学研究的全部潜力。
Two‐photon polymerization (TPP) is widely used to create 3D micro‐ and nanoscale scaffolds for biological and mechanobiological studies, which often require the mechanical characterization of the TPP fabricated structures. To satisfy physiological requirements, most of the mechanical characterizations need to be conducted in liquid. However, previous characterizations of TPP fabricated structures are all conducted in air due to the limitation of conventional micro‐ and nanoscale mechanical testing methods. In this study, a new experimental method is reported for testing the mechanical properties of TPP‐printed microfibers in liquid. The experiments show that the mechanical behaviors of the microfibers tested in liquid are significantly different from those tested in air. By controlling the TPP writing parameters, the mechanical properties of the microfibers can be tailored over a wide range to meet a variety of mechanobiology applications. In addition, it is found that, in water, the plasticly deformed microfibers can return to their predeformed shape after tensile strain is released. The shape recovery time is dependent on the size of microfibers. The experimental method represents a significant advancement in mechanical testing of TPP fabricated structures and may help release the full potential of TPP fabricated 3D tissue scaffolds for mechanobiological studies.