Synthesis of brominated directly fused diporphyrins through gold(III)-mediated oxidation.
Synthesis of brominated directly fused diporphyrins through gold(III)-mediated oxidation.
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DOI：
10.1021/ol061763f
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发表时间：
2006-08
期刊：
影响因子：
5.2
通讯作者：
A. Sahoo;Yasuyuki Nakamura;N. Aratani;Kil Suk Kim;S. Noh;H. Shinokubo;Dongho Kim;A. Osuka
中科院分区：
文献类型：
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作者：
A. Sahoo;Yasuyuki Nakamura;N. Aratani;Kil Suk Kim;S. Noh;H. Shinokubo;Dongho Kim;A. Osuka
通过AuCl₃ - AgOTf组合介导的高效氧化偶联反应，已成功实现了中位、中位 - 二溴双稠合和三稠合双卟啉的高效合成。此外，还开发了钯催化的中位 - 溴卟啉脱溴反应。该脱溴方法能够将溴作为卟啉活性中位的保护基加以应用。
Highly efficient synthesis of meso,meso-dibromo doubly and triply fused diporphyrins has been achieved through a powerful oxidative coupling mediated by AuCl3-AgOTf combination. In addition, palladium-catalyzed debromination of meso-bromoporphyrins has been developed. This debromination protocol enables employment of bromine as a protecting group for the reactive meso-position of porphyrins.