Electrostatic dominoes: long distance propagation of mutational effects in photosynthetic reaction centers of Rhodobacter capsulatus.
Electrostatic dominoes: long distance propagation of mutational effects in photosynthetic reaction centers of Rhodobacter capsulatus.
复制标题
静电多米诺骨牌：荚膜红杆菌光合反应中心突变效应的长距离传播。
DOI：
10.1021/bi00026a021
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发表时间：
1995
期刊：
影响因子：
2.9
通讯作者：
Hanson,DK
中科院分区：
文献类型：
--
作者：
Sebban,P;Maróti,P;Schiffer,M;Hanson,DK
Revised Manuscript Received April 10, 1995® abstract: Two point mutants from the purple bacterium Rhodobacter capsulatus, both modified in the M protein of the photosynthetic reaction center, have been studied by flash-induced absorbance spectroscopy. These strains carry either the M231Arg—Leu or M43Asn—Asp mutations, which are located 9 and 15 Á, respectively, from the terminal electron acceptor Qb. In the wild-type Rb. sphaeroides structure, M231Arg is involved in a conserved salt bridge with H125Glu and H232Glu and M43Asn is located among several polar residues that form or surround the Qb binding site. Thesesubstitutions were originally uncovered in phenotypic revertants isolated from the photosynthetically incompetent L212Glu-L213Asp—-
