Central somatosensory conduction time in comatose patients
Central somatosensory conduction time in comatose patients
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昏迷患者中枢体感传导时间
DOI：
10.1002/ana.410050412
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发表时间：
1979
影响因子：
11.2
通讯作者：
D. Hume
中科院分区：
文献类型：
--
作者：
PhD L. Hume;M. F. B. R. Cant;MA N. A. Shaw;D. Hume
背柱核和大脑皮层之间的体感传导时间可以在正中神经刺激后通过记录头皮和颈部的诱发电位来测量。在24例昏迷患者中，11例中枢传导时间相对于正常值（5.6 ± 0.5 msec）显著增加。结果昏迷发生后10天和35天内与最终预后相关。传导时间与血清苯巴比妥（0 - 630 μmol/L）和中心体温（35.0 - 38.5°C）无关。昏迷的系列研究表明：（1）在暂时性代谢紊乱期间短期增加，（2）持续增加，并在许多个月内逐渐恢复，特别是在头部受伤后。
Somatosensory conduction time between the dorsal column nuclei and the cerebral cortex may be measured following median nerve stimulation by recording evoked potentials from both scalp and neck. Central conduction times were significantly increased relative to normal (5.6 ± 0.5 msec) in 11 of 24 comatose patients. Results within 10 and 35 days of onset of coma were correlated with the final outcome. Conduction times were independent of serum phenobarbital (0 to 630 μmol per liter) and of central body temperature (35.0 to 38.5°C). Serial studies in coma demonstrated (1) short‐term increases during temporary metabolic disorders, and (2) sustained increases with gradual recovery over many months, particularly after head injury.