Initial Observations of COVID-19 in US Children.
Initial Observations of COVID-19 in US Children.
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DOI：
10.1542/hpeds.2020-000257
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发表时间：
2020-10-01
影响因子：
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通讯作者：
Avner, Jeffrey R
中科院分区：
文献类型：
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作者：
Agha, Rabia;Kojaoghlanian, Tsoline;Avner, Jeffrey R
在世界范围内，冠状病毒病(新冠肺炎)对儿童和成人的影响不同。有关儿童感染的临床表现的数据有限。我们提供了在我们机构感染严重急性呼吸综合征冠状病毒2型病毒的儿科住院患者在广泛的局部传播期间的详细描述，旨在了解疾病的表现和结果。对年龄在0-18岁的儿童进行了回顾性分析，在4周的时间里，在收治的鼻咽标本中进行了严重急性呼吸综合征冠状病毒2型聚合酶链式反应阳性试验。我们介绍了22名患者的临床数据，并强调了报告的可变性。在我们的研究中，大多数儿童没有出现呼吸系统疾病或新冠肺炎的症状；许多儿童只是因为普遍的检测而被发现。由于儿童可能会有不同的新冠肺炎感染体征和症状，因此靶向检测可能会漏掉一些病例。
Coronavirus disease (COVID-19) has affected children differently from adults worldwide. Data on the clinical presentation of the infection in children are limited. We present a detailed account of pediatric inpatients infected with severe acute respiratory syndrome coronavirus 2 virus at our institution during widespread local transmission, aiming to understand disease presentation and outcomes. A retrospective chart review was performed of children, ages 0 to 18 years, with a positive polymerase chain reaction test for severe acute respiratory syndrome coronavirus 2 on nasopharyngeal specimens admitted to our hospital over a 4-week period. We present clinical data from 22 patients and highlight the variability of the presentation. In our study, most children presented without respiratory illness or symptoms suggestive of COVID-19; many were identified only because of universal testing. Because children may have variable signs and symptoms of COVID-19 infection, targeted testing may miss some cases.