TREATMENT OF PORT-WINE STAINS WITH THE FLASHLAMP-PUMPED PULSED DYE-LASER - EXTENDED CLINICAL-EXPERIENCE IN CHILDREN AND ADULTS
TREATMENT OF PORT-WINE STAINS WITH THE FLASHLAMP-PUMPED PULSED DYE-LASER - EXTENDED CLINICAL-EXPERIENCE IN CHILDREN AND ADULTS
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DOI：
10.1097/00000637-199405000-00007
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发表时间：
1994-05-01
影响因子：
1.5
通讯作者：
WILSON, F
中科院分区：
文献类型：
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作者：
ALSTER, TS;WILSON, F
76 名患有鲜红斑痣 (PWS) 的患者（51 名女性，25 名男性）接受了闪光灯泵浦脉冲染料激光（585 nm，450 musec）治疗。患者年龄从 1 个月到 71 岁不等（平均 14 岁）。在平均 9.0 次（范围，4-15 次）激光治疗后，接受研究的所有患者中，49% 的患者的光亮反应达到 90% 或更好（平均 94.6%）。总体而言，平均 9.1 次（范围：2-19 次）激光治疗后临床改善达 79%。与之前的研究相比，大龄儿童（9-15岁）和成人（>16岁）获得PWS清除所需的治疗次数并不显着多于婴儿（0-2岁）和幼儿（3-8岁）治疗PWS所需的治疗次数。事实上，3至8岁儿童的PWS需要最多次数的激光治疗，这可能是由于儿童生长过程中构成病变的扩张血管持续异常生长所致。此外，清除不同身体部位的 PWS 所需的激光治疗次数似乎没有显着差异。虽然 585 nm 脉冲染料激光仍然是去除儿童和成人 PWS 的首选治疗方法，但在所有年龄组中获得病变清除所需的治疗次数比之前报道的要多。
Seventy-six patients (51 females, 25 males) with port-wine stains (PWS) were treated with the flashlamp-pumped pulsed dye laser (585 nm, 450 musec). The patients ranged in age from 1 month to 71 years (average, 14 yr). Forty-nine percent of all patients under study had a 90% or better (average, 94.6%) lightening response after an average of 9.0 (range, 4-15) laser treatments. Overall, there was a 79% clinical improvement seen after an average of 9.1 (range, 2-19) laser treatments. In contrast to previous studies, the number of treatments necessary to obtain PWS clearing in older children (9-15 yr) and adults (>16 yr) was not significantly greater than the number required to treat PWS in infants (0-2 yr) and younger children (3-8 yr). In fact, PWS in children aged 3 to 8 years required the greatest number of laser treatments, which may be due to continued abnormal growth of the ectatic blood vessels comprising the lesion during the growth of the child. In addition, there did not appear to be a significant difference in the number of laser treatments necessary to obtain clearing of PWS in different body locations. While the 585 nm pulsed dye laser continues to be the treatment of choice for removal of PWS in children and adults, the number of treatments necessary to obtain lesional clearing in all age groups is greater than previously reported.