Identification of prenyl flavonoid glycosides and phenolic acids in Epimedium koreanum Nakai by Q-TOF-MS combined with selective enrichment on "click oligo (ethylene glycol)" column
Identification of prenyl flavonoid glycosides and phenolic acids in Epimedium koreanum Nakai by Q-TOF-MS combined with selective enrichment on "click oligo (ethylene glycol)" column
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DOI：
10.1016/j.jpba.2009.09.033
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发表时间：
2010-02-05
影响因子：
3.4
通讯作者：
Liang, Xinmiao
中科院分区：
文献类型：
--
作者：
Wang, Yaqin;Guo, Zhimou;Liang, Xinmiao
戊烯基类黄酮苷和酚酸是药用植物淫羊藿（Epimedium koreanum Nakai， EK）的主要成分。利用超高效液相色谱- Q-TOF-MS结合“click oligo（乙二醇）”（click OEG）色谱柱，建立了一种富集和鉴定这些化合物的有效方法。用该方法鉴定或初步鉴定了51种戊烯基类黄酮苷和18种酚酸。其中，11个烯丙基类黄酮苷为新化合物，4个酚酸为新化合物，7个酚酸为新鉴定。因此，MS结合选择性富集为分析戊烯基类黄酮苷和酚酸提供了强有力的手段。(C) 2009 Elsevier B.V.版权所有
Prenyl flavonoid glycosides and phenolic acids are constituents of the medicinal plant Epimedium koreanum Nakai (EK). An efficient method was developed to enrich these compounds and identify them, using ultra performance liquid chromatography combined with Q-TOF-MS, and a "click oligo (ethylene glycol)" (Click OEG) column. Using this method, 51 prenyl flavonoid glycosides and 18 phenolic acids were identified or tentatively identified. Of these, 11 prenyl flavonoid glycosides and 4 phenolic acids were new compounds, and 7 phenolic acids were newly identified in EK. Therefore, MS combined with selective enrichment provided a powerful means for analyzing prenyl flavonoid glycosides and phenolic acids. (C) 2009 Elsevier B.V. All rights reserved.