Growth factors in mammary gland function.

Growth factors in mammary gland function.
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乳腺功能中的生长因子。

DOI:
10.1530/jrf.0.0850759
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发表时间:
1989
期刊:
Journal of reproduction and fertility
影响因子:
--
通讯作者:
I. Forsyth
I. Forsyth
中科院分区:
--
文献类型:
--
作者:
I. Forsyth

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产生足够数量的初乳和乳汁对于大多数哺乳动物幼崽的生存至关重要。乳腺为哺乳所做的准备贯穿胎儿和产后的整个过程,是许多复杂相互作用的结果。它涉及腺体从胎儿的上皮原基通过形成分支管状结构转变为完全发育的小叶肺泡腺,该腺体已获得产生乳蛋白、脂肪和糖的分化能力,并通过乳汁排出将这些物质输送给乳儿。乳腺发育已被广泛综述(参见 Cowie 等人,1980;Mepham,1983;Knight,1984;Tucker,1987,了解最近的综述和进一步的参考文献)。乳腺的产量取决于上皮细胞的数量及其运输、合成和分泌乳汁成分的能力。细胞数量和细胞或肺泡单位的分泌能力之间的平衡决定了泌乳曲线的形状(Knight & Wilde,1987)。这部分是由全身内分泌因素决定的,但越来越明显的是,存在很大程度的局部控制。
Production of colostrum and milk in adequate quantities is essential for the survival of the young of most mammals. Preparation of the mammary gland for lactation takes place throughout fetal and post-natal life and results from many complex interactions. It involves the transformation of the gland from an epithelial anlagen in the fetus, through formation of a branched tubular structure to the fully developed lobulo-alveolar gland which has acquired the differentiated capacity to produce milk proteins, fat and sugar and, by milk ejection, to deliver these to the suckling. Mammary development has been reviewed extensively (see Cowie et al., 1980; Mepham, 1983; Knight, 1984; Tucker, 1987, for recent reviews and further references). The yield of the mammary gland is determined by numbers of epithelial cells and by their ability to transport, synthesize and secrete milk components. The balance between cell number and the secretory capacity of cells or alveolar units determines the shape of the lactation curve (Knight & Wilde, 1987). This is in part determined by systemic endocrine factors but it is increasingly evident that there is a large measure of local control.
肝素结合内皮细胞生长因子的纯化和表征。
DOI: --
发表时间: 1986
期刊: The Journal of biological chemistry
影响因子: --
作者:
Lobb,R;Sasse,J;Sullivan,R;Shing,Y;D'Amore,P;Jacobs,J;Klagsbrun,M
通讯作者: Klagsbrun,M
不同生理状态下小鼠乳腺表皮生长因子受体水平。
DOI: 10.1210/endo-117-1-405
发表时间: 1985
期刊: Endocrinology
影响因子: 4.8
作者:
Edery,M;Pang,K;Larson,L;Colosi,T;Nandi,S
通讯作者: Nandi,S
生长调节素-C 替代胰岛素,用于在无血清胶原凝胶细胞培养物中生长正常处女小鼠的乳腺上皮细胞。
DOI: 10.1210/endo-119-6-2695
发表时间: 1986
期刊: Endocrinology
影响因子: 4.8
作者:
Imagawa,W;Spencer,EM;Larson,L;Nandi,S
通讯作者: Nandi,S
DOI: 10.1073/pnas.83.8.2496
发表时间: 1986-04-01
影响因子: 11.1
作者:
BERTHOIS, Y;KATZENELLENBOGEN, JA;KATZENELLENBOGEN, BS
通讯作者: KATZENELLENBOGEN, BS