Enhanced enantioselectivity and remarkable acceleration on the lipase-catalyzed transesterification using novel ionic liquids
Enhanced enantioselectivity and remarkable acceleration on the lipase-catalyzed transesterification using novel ionic liquids
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DOI：
10.1039/b405396f
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发表时间：
2004-01-01
期刊：
影响因子：
9.8
通讯作者：
Hayase, S
中科院分区：
文献类型：
--
作者：
Itoh, T;Han, SH;Hayase, S
以十六烷基硫酸聚氧乙烯酯（10）为原料合成了咪唑盐离子液体，并将其作为脂肪酶催化酯交换反应的添加剂，在异丙醚或正己烷溶剂体系中，添加3 ~ 10mol%的咪唑盐离子液体可显著提高洋葱假单胞菌脂肪酶催化1-苯基乙醇与乙酸乙烯酯的酯交换反应的对映选择性.当脂肪酶被这种新型的离子液体涂覆，并用作催化剂，在i-Pr 2 O或在己烷中的酯交换反应时，有一个显着的加速。
Novel imidazolium salt ionic liquids were prepared derived from polyoxyethylene( 10) cetyl sulfate and used as an additive for lipase-catalyzed transesterification in organic solvent; a remarkable enhanced enantioselectivity was obtained when the salt was added in 3 to 10 mol% vs. substrate in the Pseudomonas cepacia lipase-catalyzed transesterification of 1-phenylethanol using vinyl acetate in a diisopropyl ether or hexane solvent system. There was a remarkable acceleration when the lipase was coated with this novel ionic liquid and used as catalyst for transesterification in i-Pr2O or in hexane.