MERS-CoV: Middle East respiratory syndrome corona virus: Can radiology be of help? Initial single center experience
MERS-CoV: Middle East respiratory syndrome corona virus: Can radiology be of help? Initial single center experience
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DOI：
10.1016/j.ejrnm.2015.11.004
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发表时间：
2015-11-25
期刊：
影响因子：
--
通讯作者：
Hamimi A
中科院分区：
文献类型：
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作者：
Hamimi A
一种名为中东呼吸综合征冠状病毒（MERS-CoV）的新型冠状病毒人类感染于2012年9月首次在沙特阿拉伯和中东发现。本研究的目的是建立诊断MERS冠状病毒的最典型的放射学征象。这是一项回顾性描述性研究。所有患者均接受连续x光检查。10例患者均获得胸部高分辨率非对比CT。检查结果包括实变、磨玻璃影、结节、网状影、肺门和纵隔腺病。我们的研究共纳入12例患者，患病率为男性（2:1），年龄在18 ~ 76岁之间，平均年龄36±2岁。结果：6例平均住院时间21 ~ 35天，1例14天后死亡，5例根据当地政府规定转至中央政府医院。MERS冠状病毒在胸部x线和CT上可能有特定的表现，表现为单个或多个混浊，进展为广泛的多灶双侧磨玻璃混浊斑块或合并实变，类似于组织性肺炎。
Human infection with a novel coronavirus named Middle East respiratory syndrome coronavirus (MERS-CoV) was first identified in Saudi Arabia and the Middle East in September, 2012. The aim of this study was to establish the most pathognomonic radiological sign(s) to diagnose MERS CoV. This is a retrospective descriptive study. All patients were subjected to serial X-ray. High resolution non-contrast CT chest was also obtained for 10 patients. The scans were reviewed for findings including consolidation, ground-glass opacities, nodules, reticular opacities and hilar and mediastinal adenopathy. A total of 12 patients were included in our study with prevalence of males (2:1) with ages ranging between 18 and 76 years having an average age of 36 ± 2 years. The outcome of these patients was as follows: 6 were treated with average hospital stay ranging between 21 and 35 days, one case died after 14 days, and 5 cases were transferred to Central Governmental hospital according the local authority rules. MERS CoV virus may have a specific pattern in chest X-ray and CT developing a single or multiple opacities progressing into a widespread multifocal bilateral patches of ground glass opacities or confluent consolidation resembling organizing pneumonia.