Muscarinic M3 receptors mediate secretion from sweat glands in the rat.

Muscarinic M3 receptors mediate secretion from sweat glands in the rat.
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毒蕈碱 M3 受体介导大鼠汗腺的分泌。

DOI:
10.1016/s1043-6618(05)80082-9
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发表时间:
1991
影响因子:
9.3
通讯作者:
A. Brambilla
A. Brambilla
中科院分区:
医学1区
文献类型:
--
作者:
A. Schiavone;A. Brambilla

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我们研究了一系列毒蕈碱拮抗剂抑制大鼠唾液和汗腺毒蕈碱介导的分泌物的能力。其抑制唾液分泌的作用与抑制m3受体的作用是一致的。在它们阻断唾液腺和汗腺分泌的效力之间发现了高度显著的相关性。这些结果表明唾液腺和汗腺具有相同的毒蕈碱受体,符合m3亚型。
We investigated a series of muscarinic antagonists for their ability to inhibit muscarinic-mediated secretions from salivary and sweat glands in the rat. Their potency in blocking saliva secretion was compatible with the inhibition of M3receptors.A highly significant correlation was found between their potency in blocking secretion from both salivary and sweat glands.These results indicate that salivary and sweat glands possess the same muscarinic receptors which conform to the M3subtype.
大鼠胰腺腺泡上的毒蕈碱受体亚型:分泌和结合研究。
DOI: 10.1152/ajpgi.1986.251.2.g275
发表时间: 1986
期刊: The American journal of physiology
影响因子: --
作者:
Louie,DS;Owyang,C
通讯作者: Owyang,C
胆碱能拮抗剂在分离的大鼠胰腺腺泡中鉴定出毒蕈碱受体的亚类。
DOI: --
发表时间: 1987
期刊: The Journal of pharmacology and experimental therapeutics
影响因子: --
作者:
Korc,M;Ackerman,MS;Roeske,WR
通讯作者: Roeske,WR