A QUANTITATIVE STUDY OF THE PROJECTIONS OF THE GRACILE, CUNEATE AND TRIGEMINAL NUCLEI AND OF THE MEDULLARY RETICULAR-FORMATION TO THE THALAMUS IN THE RAT
A QUANTITATIVE STUDY OF THE PROJECTIONS OF THE GRACILE, CUNEATE AND TRIGEMINAL NUCLEI AND OF THE MEDULLARY RETICULAR-FORMATION TO THE THALAMUS IN THE RAT
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DOI：
10.1016/0306-4522(89)90115-2
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发表时间：
1989-01-01
期刊：
影响因子：
3.3
通讯作者：
WEBSTER, KE
中科院分区：
文献类型：
--
作者：
KEMPLAY, S;WEBSTER, KE
将辣根过氧化物酶注入一侧丘脑后，计数背索核和三叉神经感觉复合体中标记神经元的数量。一个比较研究的模式后，一系列的生存时间的标记，和动物注射后存活72小时被用来提供详细的定量信息的模式的分布标记的细胞。丘脑注射后，三叉神经的主要感觉核（8683个标记神经元）和三叉神经脊束核，极间部（1920）标记严重。脊髓核的口部标记更稀疏（524标记的神经元），而尾部（260标记的神经元）显示了一个层状标记模式，继续跨越脊髓交界处到上颈段。薄（2152标记的神经元）和楔（2339）核也显示喙尾变化的标记密度：中间的三分之一的每个核包含66%的标记薄和楔细胞。研究结果与已知的功能的安排，从这些核团在不同的物种的上升的感觉投射，并与以前的研究结果进行了比较，丘脑投射细胞在脊髓的上颈段的分布。
Following injection of horseradish peroxidase into the thalamus of one side, the numbers of labelled neurons in the nuclei of the dorsal funiculi and in the trigeminal sensory complex were counted. A comparative study was made of the pattern of labelling after a range of survival times, and animals surviving for 72 h after injection were used to provide detailed quantitative information about the patterns of distribution of labelled cells. The principal sensory nucleus of the trigeminal nerve (8683 labelled neurons) and the nucleus of the spinal trigeminal tract, pars interpolaris (1920) label heavily after thalamic injection. Pars oralis of the spinal nucleus labels more sparsely (524 labelled neurons), while the pars caudalis (260 labelled neurons) shows a laminar labelling pattern which continues across the spinomedullary junction into the upper cervical segments. The gracile (2152 labelled neurons) and cuneate (2339) nuclei also show rostrocaudal variation in labelling density: the middle one-third of each nucleus contains 66% of labelled gracile and cuneate cells. The findings are correlated with known features of the arrangement of the ascending sensory projections from these nuclei in various species, and are compared with previous findings on the distribution of thalamically-projecting cells in the upper cervical segments of the spinal cord.