Trichinenlides A-T, Mexicanolide-Type Limonoids from Trichilia sinensis

Trichinenlides A-T, Mexicanolide-Type Limonoids from Trichilia sinensis
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DOI:
10.1021/np400408s
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发表时间:
2013-10-01
影响因子:
5.1
通讯作者:
Yue, Jian-Min
Yue, Jian-Min
中科院分区:
生物学2区
文献类型:
--
作者:
Xu, Jin-Biao;Lin, Yuan;Yue, Jian-Min

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Twenty new mexicanolide-type limonoids, namely, trichinenlides A T (1-20), and 11 known analogues were isolated from the leaves and twigs of Trichilia sinensis. Trichinenlides B (2) and C (3) and heytrijunolide D exhibited inhibition against lipopolysaccharide-induced nitric oxide production in RAW 264.7 macrophages with IC50 values of 2.85, 1.88, and 3.33 mu M, respectively.