UK guideline for the use of HIV Post-Exposure Prophylaxis Following Sexual Exposure, 2015

UK guideline for the use of HIV Post-Exposure Prophylaxis Following Sexual Exposure, 2015
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DOI:
10.1177/0956462416641813
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发表时间:
2016-08-01
影响因子:
1.4
通讯作者:
Fisher, Martin
Fisher, Martin
中科院分区:
医学4区
文献类型:
--
作者:
Cresswell, Fiona;Waters, Laura;Fisher, Martin

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我们提出了最新的英国性健康和艾滋病毒协会的艾滋病毒暴露后预防性暴露(PEPSE)的指导方针。本文件包括对支持使用PEPSE的当前数据的审查,考虑如何计算潜在暴露后的感染风险,并提供何时应该和不应该考虑PEPSE的建议。我们还审查了哪些药物用于PEPSE,提供了初步评估的清单,并提出了监测接受PEPSE的个人的建议。特殊情况下,PEPSE的成本效益,以及有关的服务提供的问题进行了讨论。在整个文件中,考虑了PEPSE在其他艾滋病毒预防战略的更广泛背景下的位置。
We present the updated British Association for Sexual Health and HIV guidelines for HIV post-exposure prophylaxis following sexual exposure (PEPSE). This document includes a review of the current data to support the use of PEPSE, considers how to calculate the risks of infection after a potential exposure, and provides recommendations on when PEPSE should and should not be considered. We also review which medications to use for PEPSE, provide a checklist for initial assessment, and make recommendations for monitoring individuals receiving PEPSE. Special scenarios, cost-effectiveness of PEPSE, and issues relating to service provision are also discussed. Throughout the document, the place of PEPSE within the broader context of other HIV prevention strategies is considered.