Effect of weight loss on erectile function in men with overweight or obesity: A meta-analysis of randomised controlled trials
Effect of weight loss on erectile function in men with overweight or obesity: A meta-analysis of randomised controlled trials
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DOI：
10.1111/and.14250
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发表时间：
2021-10-13
期刊：
影响因子：
2.4
通讯作者：
Jiang, Hongyang
中科院分区：
文献类型：
--
作者：
Li, Hao;Xu, Wenchao;Jiang, Hongyang
肥胖和超重是勃起功能障碍（ED）的独立危险因素。减肥是否能改善勃起功能还存在争议。因此，我们进行了这项荟萃分析，以阐明体重减轻对超重或肥胖男性勃起功能的治疗效果。在Cochrane Library、Embase、Web of Science、PubMed等数据库进行文献检索，获取2021年3月1日前发表的所有相关英文文章。主要结局是最终的国际勃起功能指数（IIEF）评分或IIEF评分的变化。次要结局是最终体重和体重指数（BMI）或体重和BMI的变化。筛选后，我们的荟萃分析纳入了5项研究，共619名参与者。结果显示，减肥组与对照组体重平均差值为-18.07 kg, p < 0.01； BMI平均差值为-9.6 kg/m(2), p < 0.01。这项荟萃分析表明，减肥可以改善超重或肥胖男性的勃起功能。减肥可以作为ED的辅助治疗。
Obesity and overweight are independent risk factors of erectile dysfunction (ED). It is controversial whether weight loss can improve erectile function. We thereby performed this meta-analysis to clarify the therapeutic effect of weight loss on erectile function in overweight or obese men. Literature search was conducted on databases including Cochrane Library, Embase, Web of Science and PubMed to obtain all relevant English articles published before March 1, 2021. The primary outcome was final International Index of Erectile Function (IIEF) score or change in IIEF score. The secondary outcome was final body weight and body mass index (BMI) or change in body weight and BMI. After screening, 5 studies with 619 participants were enrolled in our meta-analysis. Our result showed that the mean difference in body weight between weight loss group and control group was -18.07 kg with p < .01, and the mean difference in BMI was -9.6 kg/m(2) with p p < .01. This meta-analysis showed that weight loss could improve erectile function in overweight or obese men. Losing weight could serve as an adjuvant therapy for ED.