Mitochondrial DNA polymorphisms in Gelao ethnic group residing in Southwest China
Mitochondrial DNA polymorphisms in Gelao ethnic group residing in Southwest China
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DOI：
10.1016/j.fsigen.2010.04.007
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发表时间：
2011-01-01
影响因子：
3.1
通讯作者：
Kong, Qing-Peng
中科院分区：
文献类型：
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作者：
Liu, Chang;Wang, Sha-Yan;Kong, Qing-Peng
仡佬族是我国西南地区的一个土著民族，其历史经历了一个漫长而复杂的演变过程。为探讨这一古老民族的遗传结构，本研究收集了102个仡佬族个体的线粒体DNA（mtDNA）多态性，并对其进行了分析。利用控制区高变区I和II以及一些必要的编码区片段所提供的信息，通过划分不同的单倍型群，确定了所有mtDNA的系统发育地位。南方流行的单倍群B、R9和M7占基因库的45.1%，而北方流行的单倍群A、D、G、N9和M8占39.2%。单倍型群分布表明，仡佬族具有南方群体的特征，并具有一定的地域性。在PC图中，仡佬族与百越族、当地汉族和苗族聚在一起。研究结果表明了仡佬族群体的复杂性，可以很好地补充中国mtDNA数据库。(C)2010爱思唯尔爱尔兰有限公司版权所有。
Gelao ethnic group, an aboriginal population residing in southwest China, has undergone a long and complex evolutionary process. To investigate the genetic structure of this ancient ethnic group, mitochondrial DNA (mtDNA) polymorphisms of 102 Gelao individuals were collected and analyzed in this study. With the aid of the information extracted from control-region hypervariable segments (HVSs) I and II as well as some necessary coding-region segments, phylogenetic status of all mtDNAs under study were determined by means of classifying into various defined haplogroups. The southern-prevalent haplogroups B, R9, and M7 account for 45.1% of the gene pool, whereas northern-prevalent haplogroups A, D, G, N9, and M8 consist of 39.2%. Haplogroup distribution indicates that the Gelao bears signatures of southern populations and possesses some regional characters. In the PC map, Gelao clusters together with populations with Bai-Yue tribe origin as well as the local Han and the Miao. The results demonstrate the complexity of Gelao population and the data can well supplement the China mtDNA database. (C) 2010 Elsevier Ireland Ltd. All rights reserved.