Large volume osteosarcomas of the femur treated with total femoral replacement.
Large volume osteosarcomas of the femur treated with total femoral replacement.
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DOI：
10.5704/moj.1403.015
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发表时间：
2014-03
影响因子：
0.7
通讯作者：
Tan S
中科院分区：
文献类型：
--
作者：
Pan K;Chan W;Shanmugam P;Ong G;Kamaruddin F;Tan S
有广泛恶性肿瘤累及股骨的患者，当其肢体可以保留时，通常需要全股骨置换术。报道的系列病例较少，且涉及肿瘤的异质性。我们报告了2003年至2010年间在我院治疗的9例股骨骨肉瘤患者，平均随访27个月（6至56个月）。年龄从9岁到17岁不等（平均14岁）。他们的肿瘤体积大（平均911 cm3），出现较晚，从症状出现到最终治疗平均为5.5个月。所有患者均行手术切除和全股骨置换术。截至本报告时，已有6名患者死亡，2名存活，功能良好。1例因随访而丢失。这些患者需要高水平的治疗护理，预后不佳。大骨肉瘤，股骨，全股置换
Patients with extensive malignancies involving the femur often require total femoral replacement when their limbs can be salvaged. Reported series are small and involve heterogeneity of tumours. We present nine patients with osteosarcomas of the femur treated at our institution between 2003 and 2010 with a mean follow-up of 27 (6 to 56) months. Their ages ranged from 9 to 17 (mean 14 years). They had large volume tumours (mean 911 cm3) and presented late with a mean of 5.5 months from the onset of symptoms to definitive treatment. All patients underwent resection and total femur replacement. Six patients have died and two are alive with good function at the time of this report. One was lost to follow-up. These patients require a high level of treatment care and have a guarded prognosis. Large osteosarcomas, femur, total femoral replacement