Single-molecule studies of DNA mechanics
Single-molecule studies of DNA mechanics
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DOI:
10.1016/s0959-440x(00)00085-3
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发表时间:
2000-06-01
影响因子:
6.8
通讯作者:
Smith, D
中科院分区:
文献类型:
--
作者:
Bustamante, C;Smith, SB;Smith, D
During the past decade, physical techniques such as optical tweezers and atomic force microscopy were used to study the mechanical properties of DNA at the single-molecule level. Knowledge of DNA's stretching and twisting properties now permits these single-molecule techniques to be used in the study of biological processes such as DNA replication and transcription.