Stereoselective construction of substituted chromans by palladium-catalyzed cyclization of propargylic carbonates with 2-(2-hydroxyphenyl)acetates.
Stereoselective construction of substituted chromans by palladium-catalyzed cyclization of propargylic carbonates with 2-(2-hydroxyphenyl)acetates.
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DOI：
10.1021/ol901964z
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发表时间：
2009-09
期刊：
影响因子：
5.2
通讯作者：
Masahiro Yoshida;M. Higuchi;K. Shishido
中科院分区：
文献类型：
--
作者：
Masahiro Yoshida;M. Higuchi;K. Shishido
通过钯催化的丙叉碳酸酯和2-(2-羟基苯基)乙酸酯的反应，以高度立体选择性的方式构建了高度取代的色曼。对映体选择性反应也成功地进行了，得到了具有高对映体选择性的光学活性色曼。
Highly substituted chromans have been constructed in a highly stereoselective manner by a palladium-catalyzed reaction of propargylic carbonates with 2-(2-hydroxyphenyl)acetates. Enantioselective reactions also successfully proceeded to give the optically active chromans with high enantioselectivity.