Synthesis of fused imidazole rings by sequential van Leusen/C-H bond activation
Synthesis of fused imidazole rings by sequential van Leusen/C-H bond activation
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DOI：
10.1016/j.tetlet.2006.10.051
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发表时间：
2006-12-11
影响因子：
1.8
通讯作者：
Djuric, Stevan W.
中科院分区：
文献类型：
--
作者：
Gracias, Vijaya;Gasiecki, Alan F.;Djuric, Stevan W.
报道了一种利用货车Leusen三组分反应，然后通过Pd/Cu催化的分子内Garylation反应来获得稠合咪唑环的简明路线。发现该反应是一般性的，并且使用两步反应顺序以中等至优异的产率形成产物。(c)2006爱思唯尔有限公司保留所有权利。
A concise route to access fused imidazole rings employing the van Leusen three-component reaction followed by a Pd/Cu catalyzed intramolecular Garylation is reported. The reaction was found to be general and the products were formed in moderate to excellent yields using the two-step reaction sequence. (c) 2006 Elsevier Ltd. All rights reserved.