Outpatient respiratory outcomes in children with BPD on supplemental oxygen.
Outpatient respiratory outcomes in children with BPD on supplemental oxygen.
复制标题
BPD 儿童吸氧后的门诊呼吸结果。
DOI：
10.1002/ppul.26356
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发表时间：
2023
影响因子：
3.1
通讯作者：
McGrath-Morrow,SharonA
中科院分区：
文献类型：
--
作者：
McGlynn,JulianneR;Aoyama,BriannaC;Martin,Amanda;Collaco,JosephM;McGrath-Morrow,SharonA
前言：患有支气管肺发育不良（BPD）的早产儿经常需要在门诊进行辅助供氧。在这项研究中，我们试图确定患者的特征和人口统计学相关的需要，在最初的医院出院时，补充氧气的释放时间，并补充氧气的水平和呼吸系统症状的可能性和急性护理使用在outpatientsetting.MethodsA的BPD患者的回顾性分析与补充氧气（O2）进行。2008年至2021年间，从约翰·霍普金斯大学和费城儿童医院的门诊招募了受试者。通过图表审查和照顾者questionnaire. ResultsBPD儿童接受≥1 L的O2更有可能有严重的BPD，肺动脉高压，并在最初的出院年龄。与低O2组相比，高O2补充组的儿童出院后断奶到室内空气的速度较慢（p< 0.001）。此外，在门诊环境中，胃造口术管和吸入性皮质类固醇处方的儿童，公共保险或家庭收入较低的儿童，脱机补充O2延迟。出院时补充O2的水平并没有影响门诊急性护理使用或呼吸道症状。ConclusionBPD严重程度和水平的补充氧气使用在出院时并不与随后的急性护理使用或呼吸道症状的儿童BPD。然而，O2脱机与社会经济地位和呼吸系统药物使用显著相关，导致门诊患者O2脱机的变异性。
IntroductionPreterm children with bronchopulmonary dysplasia (BPD) frequently require supplemental oxygen in the outpatient setting. In this study, we sought to determine patient characteristics and demographics associated with need for supplemental oxygen at initial hospital discharge, timing to supplemental oxygen liberation, and associations between level of supplemental oxygen and likelihood of respiratory symptoms and acute care usage in the outpatient setting.MethodsA retrospective analysis of subjects with BPD on supplemental oxygen (O2) was performed. Subjects were recruited from outpatient clinics at Johns Hopkins University and the Children's Hospital of Philadelphia between 2008 and 2021. Data were obtained by chart review and caregiver questionnaires.ResultsChildren with BPD receiving ≥1 L of O2were more likely to have severe BPD, pulmonary hypertension, and be older at initial hospital discharge. Children discharged on higher levels of supplemental O2were slower to wean to room air compared to lower O2groups (p< 0.001). Additionally, weaning off supplemental O2in the outpatient setting was delayed in children with gastrostomy tubes and those prescribed inhaled corticosteroids, on public insurance or with lower household incomes. Level of supplemental O2at discharge did not influence outpatient acute care usage or respiratory symptoms.ConclusionBPD severity and level of supplemental oxygen use at discharge did not correlate with subsequent acute care usage or respiratory symptoms in children with BPD. Weaning of O2however was significantly associated with socioeconomic status and respiratory medication use, contributing to the variability in O2weaning in the outpatient setting.