Rapid Assessment of Water Toxicity by Plasmonic Nanomechanical Sensing

Rapid Assessment of Water Toxicity by Plasmonic Nanomechanical Sensing
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利用等离子体纳米机械传感技术快速评估水毒性

DOI:
10.1021/acs.analchem.9b04476
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发表时间:
2020-01-07
影响因子:
7.4
通讯作者:
Liu, Xian-Wei
Liu, Xian-Wei
中科院分区:
化学1区
文献类型:
--
作者:
Liu, Yi-Nan;Chen, Hai-Bo;Liu, Xian-Wei

文献摘要

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The ability to rapidly and accurately detect water toxicity is crucial for monitoring water quality and assessing toxic risk, but such detection remains a great challenge. Here, we present a plasmonic nanomechanical sensing (PNMS) system for the rapid assessment of water toxicity. This technique is based on the plasmonic sensing of the nanomechanical movement of single bacterial cells, which could be inhibited upon exposure to potential toxicants. By correlating the amplitude of nanomechanical movement with bacterial activity, we detected a variety of toxic substances in water. The direct readout of bacterial activity via PNMS allowed for a high sensitivity to toxicants in water, thereby enabling us to evaluate the acute toxicological effect of chemical compounds rapidly. The PNMS method is promising for online alerts of water quality safety and for assessing chemical hazards. We anticipate that PNMS is also suitable for a wide range of other applications, including bacterial detection and high-throughpift screening of antibacterial materials.