On cytochrome, a respiratory pigment, common to animals, yeast, and higher plants
On cytochrome, a respiratory pigment, common to animals, yeast, and higher plants
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DOI：
10.1098/rspb.1925.0039
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发表时间：
1925-08-01
期刊：
影响因子：
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通讯作者：
Keilin, D
中科院分区：
文献类型：
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作者：
Keilin, D
以myohæmatin和histohæmatin命名的MacMunn（1884-1886）描述了一种呼吸色素，他在动物王国中几乎所有目的肌肉和其他组织中都发现了这种色素。他发现，这种颜料在还原状态下，给出了一个特征光谱，有四个吸收带占据以下位置：615-593/567·5-561/554·5-546/532-511 /。当氧化时，色素不显示吸收带。1887年，MacMunn描述了一种从鸟类和哺乳动物的肌肉中以“改良形式”提取维生素d的方法。他发现鸽子的胸肌是提取“myohæmatin”最合适的材料，因为他相信这是鸽子因失血过多而死亡的肌肉中唯一的着色物质。从这个“修饰的myohæmatin”中，他还得到了其他衍生物，如酸性的hæmatin和hæmatoporphyrin，他最终得出myo-和histohæmatin是不同的呼吸色素，独立于hæmoglobin及其衍生物。1889年，Levy小心翼翼地重复了MacMunn的实验，从鸟类和哺乳动物的肌肉中提取myh æmatin，并获得了MacMunn称之为“改良myh æmatin”的物质。但他认为这种物质是由hæ血红蛋白衍生而来的一种普通的hæ色素原。
Under the names myohæmatin and histohæmatin MacMunn (1884-1886) described a respiratory pigment, which he found in muscles and other tissues of representatives of almost all the orders of the animal kingdom. He found that this pigment, in the reduced state, gives a characteristic spectrum, with four absorption bands occupying the following positions: 615—593/567·5—561/554·5—546/532—511/. When oxidized, the pigment does not show absorption bands. In 1887 MacMunn described a method by which it can be extracted in a “modified form” from the muscles of birds and mammals. He found the pectoral muscle of a pigeon to be the most suitable material for the extraction of “myohæmatin,” in the belief that it was the sole colouring matter of the muscles in a pigeon bled to death. From this “modified myohæmatin” he also obtained other derivatives, such as acid hæmatin and hæmatoporphyrin, and he finally arrived at the conclusion that myo- and histohæmatin are respiratory pigments different and independent from hæmoglobin and its derivatives. In 1889 Levy carefully repeated MacMunn’s experiments in extracting myohæmatin from muscles of birds and mammals and obtained the substance described by MacMunn as “modified myohæmatin." But he regarded this substance as an ordinary hæmochromogen, derived from hæmoglobin.