Differences Between MEG and High-Density EEG Source Localizations Using a Distributed Source Model in Comparison to fMRI
Differences Between MEG and High-Density EEG Source Localizations Using a Distributed Source Model in Comparison to fMRI
复制标题
DOI：
10.1007/s10548-014-0405-3
复制
发表时间：
2015-01-01
期刊：
影响因子：
2.7
通讯作者：
Focke, Niels K.
中科院分区：
文献类型：
--
作者：
Klamer, Silke;Elshahabi, Adham;Focke, Niels K.
脑电图（EEG）和脑磁图（MEG）被广泛用于定位大脑活动，它们的空间分辨率已经在一些出版物中进行了比较。虽然大多数临床研究表明MEG源定位的准确性更高，但模拟研究表明，对于相同数量的通道，EEG比MEG定位更准确。然而，研究比较真实的MEG和EEG数据与同等数量的通道是稀缺的。我们调查了14名右利手健康受试者在MEG，高密度-（HD-）EEG和fMRI中执行运动任务，以及在MEG和HD-EEG中执行体感任务，并比较了不同头部模型之间的诱发脑活动的源分析结果。使用单独的头部模型，HD-EEG定位显着更接近功能磁共振成像获得的解剖参考点比MEG。源分析结果是最不准确的hd-EEG的基础上，一个标准的头部模型。此外，HD-EEG和MEG定位更中间比功能磁共振成像。电源成像的定位精度取决于所使用的头部模型，其中使用个体头部模型获得更准确的结果。如果考虑到这一点，对于相同数量的通道，EEG定位可以比MEG定位更准确。
Electroencephalography (EEG) and magnetoencephalography (MEG) are widely used to localize brain activity and their spatial resolutions have been compared in several publications. While most clinical studies demonstrated higher accuracy of MEG source localization, simulation studies suggested a more accurate EEG than MEG localization for the same number of channels. However, studies comparing real MEG and EEG data with equivalent number of channels are scarce. We investigated 14 right-handed healthy subjects performing a motor task in MEG, high-density-(hd-) EEG and fMRI as well as a somatosensory task in MEG and hd-EEG and compared source analysis results of the evoked brain activity between modalities with different head models. Using individual head models, hd-EEG localized significantly closer to the anatomical reference point obtained by fMRI than MEG. Source analysis results were least accurate for hd-EEG based on a standard head model. Further, hd-EEG and MEG localized more medially than fMRI. Localization accuracy of electric source imaging is dependent on the head model used with more accurate results obtained with individual head models. If this is taken into account, EEG localization can be more accurate than MEG localization for the same number of channels.