Epidermal thickness at different body sites: Relationship to age, gender, pigmentation, blood content, skin type and smoking habits
Epidermal thickness at different body sites: Relationship to age, gender, pigmentation, blood content, skin type and smoking habits
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DOI：
10.1080/00015550310015419
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发表时间：
2003-11-01
影响因子：
3.6
通讯作者：
Wulf, HC
中科院分区：
文献类型：
--
作者：
Sandby-Moller, J;Poulsen, T;Wulf, HC
表皮厚度及其与年龄、性别、皮肤类型、色素沉着、血液含量、吸烟习惯和身体部位的关系在皮肤病学研究中很重要，本研究对其进行了研究。从71名人类志愿者的三个不同身体部位获得活组织检查，并使用防止组织损伤的制备技术在显微镜下测量角质层和细胞表皮的厚度。多元回归分析用于评估各种因素相互独立的影响。角质层的平均（SD）厚度在前臂背侧为18.3（4.9）μ m，在肩部为11.0（2.2）μ m，在前臂为14.9（3.4）μ m。细胞表皮的相应值分别为56.6（11.5）妈妈，70.3（13.6）妈妈和81.5（15.7）妈妈。身体部位在很大程度上解释了表皮厚度的变化，但也观察到显着的个体差异。角质层厚度与色素沉着呈正相关（p=0.0008），与吸烟年限呈负相关（p
Epidermal thickness and its relationship to age, gender, skin type, pigmentation, blood content, smoking habits and body site is important in dermatologic research and was investigated in this study. Biopsies from three different body sites of 71 human volunteers were obtained, and thickness of the stratum corneum and cellular epidermis was measured microscopically using a preparation technique preventing tissue damage. Multiple regressions analysis was used to evaluate the effect of the various factors independently of each other. Mean (SD) thickness of the stratum corneum was 18.3 (4.9) mum at the dorsal aspect of the forearm, 11.0 (2.2) mum at the shoulder and 14.9 (3.4) mum at the buttock. Corresponding values for the cellular epidermis were 56.6 (11.5) mum, 70.3 (13.6) mum and 81.5 (15.7) mum, respectively. Body site largely explains the variation in epidermal thickness, but also a significant individual variation was observed. Thickness of the stratum corneum correlated positively to pigmentation (p=0.0008) and negatively to the number of years of smoking (p