Investigating a safe ventilation rate for the prevention of indoor SARS transmission: An attempt based on a simulation approach

Investigating a safe ventilation rate for the prevention of indoor SARS transmission: An attempt based on a simulation approach
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DOI:
10.1007/s12273-009-9325-7
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发表时间:
2009-12-01
影响因子:
5.5
通讯作者:
Zhang, Yufeng
Zhang, Yufeng
中科院分区:
工程技术2区
文献类型:
--
作者:
Jiang, Yi;Zhao, Bin;Zhang, Yufeng

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本文确定了在医院环境中消除空气传播病毒感染和预防严重急性呼吸综合征(SARS)交叉感染的“安全通风量”。我们使用模拟方法重现了三个实际病例,在这些病例中,当SARS患者在附近的房间住院时,医院居住者报告被感染或未被感染。利用计算流体动力学(CFD)和多区域模型进行了模拟,以了解在这些情景下SARS病毒负载气溶胶的稀释水平。我们还进行了一系列的测量来验证模拟。根据这些情况确定感染和非感染的通气率(稀释水平)。消除空气中病毒感染的安全通风率是用洁净空气将SARS患者排出的空气稀释10000倍。较低体积的稀释,特别是1000倍,不足以保护未感染的人免受SARS感染,感染的风险非常高。本研究提供了一种从工程角度研究必要通风量的方法。
This paper identifies the "safe ventilation rate" for eliminating airborne viral infection and preventing cross-infection of severe acute respiratory syndrome (SARS) in a hospital-based setting. We used simulation approaches to reproduce three actual cases where groups of hospital occupants reported to be either infected or not infected when SARS patients were hospitalized in nearby rooms. Simulations using both computational fluid dynamics (CFD) and multi-zone models were carried out to understand the dilution level of SARS virus-laden aerosols during these scenarios. We also conducted a series of measurements to validate the simulations. The ventilation rates (dilution level) for infection and non-infection were determined based on these scenarios. The safe ventilation rate for eliminating airborne viral infection is to dilute the air emitted from a SARS patient by 10000 times with clean air. Dilution at lower volumes, specifically 1000 times, is insufficient for protecting non-infected people from SARS exposure and the risk of infection is very high. This study provides a methodology for investigating the necessary ventilation rate from an engineering viewpoint.