Barbamide, a chlorinated metabolite with molluscicidal activity from the Caribbean cyanobacterium Lyngbya majuscula
Barbamide, a chlorinated metabolite with molluscicidal activity from the Caribbean cyanobacterium Lyngbya majuscula
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DOI：
10.1021/np960085a
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发表时间：
1996-04-01
影响因子：
5.1
通讯作者：
Gerwick, WH
中科院分区：
文献类型：
--
作者：
Orjala, J;Gerwick, WH
The lipid extract from a Curacao collection of the marine cyanobacterium Lyngbya majuscula was toxic to the mollusc Biomphalaria glabrata. Subsequent bioassay-guided fractionation of this extract yielded a novel Lipopeptide, barbamide, as the active compound (LC(100) = 10 mu g/mL). The structure of barbamide was determined by spectroscopic methods and was found to contain several unique structural features, including a trichloromethyl group and the methyl enol ether of a beta-keto amide.
