Representation of action-specific reward values in the striatum
Representation of action-specific reward values in the striatum
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DOI：
10.1126/science.1115270
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发表时间：
2005-11-25
期刊：
影响因子：
56.9
通讯作者：
Kimura, M
中科院分区：
文献类型：
--
作者：
Samejima, K;Ueda, Y;Kimura, M
对一个行动将产生的回报的估计在决策中至关重要。为了阐明基底神经节在这一过程中的作用，我们记录了猴子的纹状体神经元，这些猴子根据估计的奖励概率在左和右手柄转向之间进行选择。在选择之前的延迟期内，超过三分之一的纹状体投射神经元的活动对两个动作之一的值具有选择性。更少的神经元被调整到相对值或动作选择。这些结果表明纹状体中的动作值的表示，这可以指导基底神经节回路中的动作选择。
The estimation of the reward an action will yield is critical in decision-making. To elucidate the role of the basal ganglia in this process, we recorded striatal neurons of monkeys who chose between left and right handle turns, based on the estimated reward probabilities of the actions. During a delay period before the choices, the activity of more than one-third of striatal projection neurons was selective to the values of one of the two actions. Fewer neurons were tuned to relative values or action choice. These results suggest representation of action values in the striatum, which can guide action selection in the basal ganglia circuit.