Three novel degraded steroids from cultures of the Basidiomycete Antrodiella albocinnamomea
Three novel degraded steroids from cultures of the Basidiomycete Antrodiella albocinnamomea
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来自担子菌 Antrodiella albocinnamomea 培养物的三种新型降解类固醇
DOI：
10.1016/j.steroids.2014.05.008
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发表时间：
2014-09-01
期刊：
影响因子：
2.7
通讯作者：
Liu, Ji-Kai
中科院分区：
文献类型：
--
作者：
Chen, Zi-Ming;Yang, Xiao-Yan;Liu, Ji-Kai
从白樟芝菌（Antrodiella albocinnamomea）中分离到三种新的降解甾体化合物，命名为白顺甾醇A-C（1-3）。通过综合光谱分析和单晶X射线晶体学确定了它们的结构。化合物2和3的混合物对蛋白酪氨酸磷酸酶1B（PTP 1B）具有明显的抑制活性。(C)2014爱思唯尔公司All rights reserved.
Three novel degraded steroids, named albocisterols A-C (1-3), have been isolated from cultures of Antrodiella albocinnamomea. Their structures were defined by comprehensive spectroscopic analysis and single crystal X-ray crystallography. The mixture of compounds 2 and 3 exhibited significant inhibitory activities against protein tyrosine phosphatase 1B (PTP1B). (C) 2014 Elsevier Inc. All rights reserved.