Open lung biopsy in Mycoplasma pneumoniae pneumonia.
Open lung biopsy in Mycoplasma pneumoniae pneumonia.
复制标题
肺炎支原体肺炎的开放肺活检。
DOI：
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发表时间：
1986
影响因子：
4.6
通讯作者：
F. Clayton
中科院分区：
文献类型：
--
作者：
Rollins Sd;T. Colby;F. Clayton
人类肺炎支原体肺炎的病理描述很少，大多数描述来自身体解剖研究。我们研究了6例确诊或疑似肺炎支原体肺炎患者的开胸肺活检标本，并回顾了文献中报道的肺炎支原体肺炎的发现，以及微生物的电子显微镜特征，以记录形态谱。我们的6例病例中有5例表现为典型但非特异性的细支气管腔内富含多形核白细胞的渗出物、排列在细支气管处的化生细胞、淋巴浆溶细胞性细支气管壁浸润物、细支气管壁周围增宽和邻近的II型肺泡细胞增生。在1例患者中，弥漫性肺泡损伤叠加在上述细支气管性病变上，6例患者为非特异性机化性肺炎。
Pathologic descriptions of Mycoplasma pneumoniae pneumonia in humans are scarce, and most descriptions are from autopsy studies. We studied open lung biopsy specimens from six patients with proved or probable M pneumoniae pneumonia and reviewed the findings on M pneumoniae pneumonia that have been reported in the literature, as well as the electron microscopic characteristics of the organism, to document the morphologic spectrum. Five of our six cases showed a typical but nonspecific polymorphonuclear leukocyte-rich exudate in the bronchiolar lumina, metaplastic cells that lined the bronchioles, a lymphoplasmacytic bronchiolar wall infiltrate, peribronchiolar septal widening, and adjacent hyperplasia of type II pneumocytes. In one patient, diffuse alveolar damage was superimposed on the above bronchiolar lesion, and the sixth patient had a nonspecific organizing pneumonia.