Coupling of alkynylTMS derivatives with vinylic iodides. An efficient route to 1,3-enynes and dienes.
Coupling of alkynylTMS derivatives with vinylic iodides. An efficient route to 1,3-enynes and dienes.
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DOI：
10.1021/ol016899m
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发表时间：
2001-11
期刊：
影响因子：
5.2
通讯作者：
J. Marshall;H. Chobanian;Mathew M. Yanik
中科院分区：
文献类型：
--
作者：
J. Marshall;H. Chobanian;Mathew M. Yanik
[反应：见正文]CuCL促进的炔基TMS衍生物与乙烯基碘的偶联反应高产率地合成了1，3-烯炔。以高丙叉醇为原料制备的烯烃经分子内硅氢化和硅基裂解得到1，3-二烯。
[reaction: see text] CuCl-promoted coupling of alkynylTMS derivatives with vinyl iodides leads to 1,3-enynes in high yield. Enynes prepared from homopropargylic alcohols undergo intramolecular hydrosilylation and subsequent silyl cleavage with TBAF to afford 1,3-dienes.