Volume reduction of cystic lesions after surgical decompression: a computerised three-dimensional computed tomographic evaluation

Volume reduction of cystic lesions after surgical decompression: a computerised three-dimensional computed tomographic evaluation
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DOI:
10.1007/s00784-012-0869-z
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发表时间:
2013-09-01
影响因子:
3.4
通讯作者:
Marchetti, Claudio
Marchetti, Claudio
中科院分区:
医学2区
文献类型:
--
作者:
Lizio, Giuseppe;Sterrantino, Anna Freni;Marchetti, Claudio

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为评价下颌骨牙源性囊性病变减压后的三维影像变化,应用三维体积测量软件分析了20例牙源性囊性病变患者减压前后的CT表现,其中角化囊肿10例,含牙囊肿9例,成釉细胞瘤1例。结果与治疗时间、年龄、性别和组织学类型有关,平均减压时间5.70(3~12)个月。减压前后平均体积分别为9.5(7.74)cm(3)和4.65(4.34)cm(3)(P<0.001),平均缩小49.86%(19.34%)。减压量与减压时间呈正相关(P<0.001),与其他变量无相关性(P=0.2357)。平均每月囊腔体积减少11.34%(平均13.52%;4.45-30.43%)(P<0.001)。这项三维CT研究证实了减压术治疗下颌牙源性囊性病变的有效性,并与治疗时间呈正相关。减压术操作简单,被患者普遍接受,是一种在手术切除前显著缩小下颌牙源性囊性病变体积的可靠方法。延长减压时间似乎可以改善还原过程的结果。
This study was performed to evaluate the three-dimensional radiographic variation in mandibular odontogenic cystic lesions after decompression.Pre- and post-decompression computed tomography (CT) evaluations in 20 patients affected by keratocysts (n = 10), dentigerous cysts (n = 9) and ameloblastoma (n = 1) were analysed using software designed for three-dimensional measurement of volumes; the results were correlated with treatment duration, age, sex and histological type.The mean (range) decompression time was 5.70 (3-12) months. The mean (SD) pre- and post-decompression volumes were 9.50 (7.74) and 4.65 (4.34) cm(3), respectively (P < 0.001), with a mean (SD) reduction of 49.86 % (19.34 %). The volume reduction was positively correlated with the duration of decompression (P < 0.001), whereas no correlations with other variables were found (P = 0.2357). The median monthly reduction in cyst volume was 11.34 % (mean, 13.52 %; range, 4.45-30.43 %) (P < 0.001).This three-dimensional CT investigation demonstrated the effectiveness of decompression in the treatment of mandibular odontogenic cystic lesions and showed a positive correlation between the duration of treatment and volume reduction.Decompression treatment, which is simple to perform and generally well-accepted by patients, is a reliable method to considerably reduce the volume of mandibular odontogenic cystic lesions before surgical removal. Extended decompression time seems to improve results of the reduction process.