Alternatives to Carbon Dioxide-Taking Responsibility for Humanely Ending the Life of Animals
Alternatives to Carbon Dioxide-Taking Responsibility for Humanely Ending the Life of Animals
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DOI：
10.3390/ani9080482
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发表时间：
2019-08-01
期刊：
影响因子：
3
通讯作者：
Weary, Dan
中科院分区：
文献类型：
--
作者：
Flammer, Shannon Axiak;Eskes, Chantra;Weary, Dan
二氧化碳长期以来一直被认为是对实验室啮齿动物实施安乐死的较好方法之一，因为它允许一次终止几只动物，不需要处理动物，易于使用，价格低廉，并且对环境友好。然而，研究表明，这种气体对啮齿动物来说是令人厌恶的，在它们有意识的时候将它们暴露在这种气体中可能是不人道的。因此，瑞士联邦食品安全和兽医局已着手寻找合适的替代品，并组织了一次会议，与会者包括参与这一过程的不同利益相关者的代表和专家，以找到解决方案。这次会议的结论是，需要一个替代者，下一步将是起草一项研究战略，以找到一个合适的替代者。二氧化碳（CO2）通常用于杀死啮齿动物。然而，大量的研究已经确定，二氧化碳对他们来说是令人厌恶的。由瑞士联邦食品安全和兽医办公室组织的多学科研讨会讨论了实验室动物安乐死协议中二氧化碳的缺点和替代品。小组集思广益会议和“世界咖啡馆”为对话提供了便利。从这一过程中得出的结论是，迫切需要二氧化碳的替代品，包括一个研究和推广计划，以满足人道杀害这些动物的需要。下一步将包括召集一组国际专家，制定、起草和公布一项关于二氧化碳替代品的研究战略。
Simple Summary Carbon dioxide has long been considered one of the better methods for euthanizing laboratory rodents because it allows termination of several animals at one time, does not require handling of the animal, is easy to use, is inexpensive, and is environmentally friendly. Research, though, has shown that this gas is aversive to rodents and that it may be inhumane to expose them to this gas while they are conscious. Therefore, the Swiss Federal Food Safety and Veterinary Office has set out to find a suitable replacement and organized a meeting that included representatives and experts of the different stakeholders involved in this process in order to find a solution. The conclusion of this meeting was that a replacement is required, and the next step would be to draft a research strategy to find a suitable replacement. Carbon dioxide (CO2) is commonly used to kill rodents. However, a large body of research has now established that CO2 is aversive to them. A multidisciplinary symposium organized by the Swiss Federal Food Safety and Veterinary Office discussed the drawbacks and alternatives to CO2 in euthanasia protocols for laboratory animals. Dialogue was facilitated by brainstorming sessions in small groups and a "World Cafe". A conclusion from this process was that alternatives to CO2 were urgently required, including a program of research and extension to meet the needs for humane killing of these animals. The next step will involve gathering a group of international experts to formulate, draft, and publish a research strategy on alternatives to CO2.