Brain activity in the prefrontal cortex during a cancellation task: effects of the target-to-distractor ratio
Brain activity in the prefrontal cortex during a cancellation task: effects of the target-to-distractor ratio
复制标题
取消任务期间前额皮质的大脑活动：目标与干扰物比率的影响
DOI：
10.1007/s00221-021-06177-7
复制
发表时间：
2021
影响因子：
2
通讯作者：
Yasumura Akira
中科院分区：
文献类型：
--
作者：
Yano Koji;Yasumura Akira
在各种临床和研究环境中，取消任务已被广泛用于神经学评估选择性注意和视觉搜索。然而，仍然缺乏证据表明任务难度水平对前额叶皮层（PFC）大脑活动的影响。本研究采用取消任务来研究不同任务难度对氧合血红蛋白（oxygenated hemoglobin，oxy-Hb）浓度的影响。基于在具有不同T/D比（即，1/9、2/8和3/7）。性能通过正确的反应，不正确的反应，命中率，成功率，和性能分数（PS）的数量进行了评估，而PFC活动进行了检查，使用近红外光谱。T/D比值最小的被试正确反应数和PS均最低。同样，我们观察到，在PFC中的oxy-Hb浓度显着增加的任务。我们的研究结果支持以前的研究，使用传统的取消任务的结果，从而表明，块设计类型是适合在相同的情况下进行考试。关于上述氧合血红蛋白浓度的变化，研究结果表明，PFC区域参与选择性注意。
Cancellation tasks have been widely used to neurologically assess selective attention and visual search in various clinical and research settings. However, there is still a lack of evidence regarding the effect of the level of task difficulty on brain activity in the prefrontal cortex (PFC). This study implemented cancellation tasks to investigate the effects of varying task difficulty on oxygenated hemoglobin (oxy-Hb) concentrations. Data from 21 healthy adults were analyzed based on performance during three-block-design types of cancellation tasks with different T/D ratios (i.e., 1/9, 2/8, and 3/7). Performance was assessed via the number of correct responses, incorrect responses, hit ratios, achievement ratios, and performance scores (PS), while PFC activity was examined using near-infrared spectroscopy. Both the numbers of correct responses and PS were the lowest for the smallestT/Dratio. Similarly, we observed that the oxy-Hb concentration in the PFC was significantly increased during the task. Our results support the findings of previous studies that used conventional cancellation tasks, thus suggesting that block design types are suitable for examinations in the same contexts. Regarding the above-mentioned changes in the oxy-Hb concentration, the findings suggest that the PFC region is involved in selective attention.