Improvements of sensorimotor processes during action cascading associated with changes in sensory processing architecture-insights from sensory deprivation.
Improvements of sensorimotor processes during action cascading associated with changes in sensory processing architecture-insights from sensory deprivation.
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DOI：
10.1038/srep28259
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发表时间：
2016-06-20
影响因子：
4.6
通讯作者：
Beste C
中科院分区：
文献类型：
--
作者：
Gohil K;Hahne A;Beste C
在大多数日常情况下，感觉运动过程是相当复杂的，因为情况往往需要按照特定的时间顺序执行几个动作；即，一个人必须级联不同的动作。虽然众所周知，刺激的变化会影响动作级联机制，但尚不清楚当感觉刺激不被操纵时，动作级联机制是否会改变，但处理这些刺激的神经结构会改变。在目前的研究中，我们使用语言前期失聪的受试者作为模型来检验这一假设，以回答这个问题。我们使用系统神经生理学方法，使用事件相关电位(ERPs)和来源定位技术。我们发现，语言前期失聪的受试者在动作级联反应中表现出改善。然而，这种改善很可能不是由于知觉(P1-ERP)和注意处理水平(N1-ERP)的变化，而是由于反应选择水平(P3-ERP)的变化。似乎颞顶交界处(TPJ)对这些效应的发生很重要，因为TPJ由重叠的网络组成，对感觉信息的处理和反应的选择非常重要。因此，感觉剥夺会影响感觉加工下游的认知过程，在需要复杂的感觉运动过程和动作级联的情况下，只有这些过程似乎对行为改善很重要。
In most everyday situations sensorimotor processes are quite complex because situations often require to carry out several actions in a specific temporal order; i.e. one has to cascade different actions. While it is known that changes to stimuli affect action cascading mechanisms, it is unknown whether action cascading changes when sensory stimuli are not manipulated, but the neural architecture to process these stimuli is altered. In the current study we test this hypothesis using prelingually deaf subjects as a model to answer this question. We use a system neurophysiological approach using event-related potentials (ERPs) and source localization techniques. We show that prelingually deaf subjects show improvements in action cascading. However, this improvement is most likely not due to changes at the perceptual (P1-ERP) and attentional processing level (N1-ERP), but due to changes at the response selection level (P3-ERP). It seems that the temporo-parietal junction (TPJ) is important for these effects to occur, because the TPJ comprises overlapping networks important for the processing of sensory information and the selection of responses. Sensory deprivation thus affects cognitive processes downstream of sensory processing and only these seem to be important for behavioral improvements in situations requiring complex sensorimotor processes and action cascading.