STUDIES ON A MUTANT OF ESCHERICHIA-COLI WITH UNBALANCED RIBONUCLEIC ACID SYNTHESIS
STUDIES ON A MUTANT OF ESCHERICHIA-COLI WITH UNBALANCED RIBONUCLEIC ACID SYNTHESIS
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DOI：
10.1128/jb.71.3.318-323.1956
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发表时间：
1956-01-01
影响因子：
3.2
通讯作者：
RYAN, A
中科院分区：
文献类型：
--
作者：
BOREK, E;ROCKENBACH, J;RYAN, A
报道了大肠杆菌菌株K12突变体在蛋氨酸饥饿下积累核糖核酸（RNA）的代谢研究。RNA富集的生物体在合成适应性酶和通常的蛋白质方面都是缓慢的。不平衡的细胞质合成RNA，不像不平衡的RNA和蛋白质合成，不是致命的。缺乏蛋氨酸的生物体中RNA的合成对辐射特别敏感。
Metabolic studies are reported on a mutant of E. coli strain K12 which accumulates ribonucleic acid (RNA) on methionine starvation. The RNA enriched organism is slow in synthesizing both adaptive enzymes and its usual proteins. Unbalanced cytoplasmic synthesis of RNA, unlike unbalanced synthesis of RNA and protein, is not lethal. The synthesis of RNA in the organism starved of methionine is uniquely sensitive to radiation.