Loss of osseointegration caused by occlusal load of oral implants - A clinical and radiographic study in monkeys
Loss of osseointegration caused by occlusal load of oral implants - A clinical and radiographic study in monkeys
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DOI：
10.1034/j.1600-0501.1996.070208.x
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发表时间：
1996-06-01
影响因子：
4.3
通讯作者：
Isidor, F
中科院分区：
文献类型：
--
作者：
Isidor, F
在猴子中评估了过度咬合负荷或牙菌斑积聚后口腔种植体周围骨的分解。将5个纯钛（Astra）螺钉型种植体植入4只猕猴（Macaca Fascicularis）的下颌骨中。在每个外侧节段放置2个种植体，在额叶区域放置1个种植体。为每只猴提供2个骨水泥夹板，分别覆盖上颌骨右侧和左侧的前磨牙和磨牙。固定装置插入后6个月，将固定部分假体安装在其中一个外侧节段的2个种植体上。修复体与拮抗夹板处于咬合上接触。在实验过程中，每个假体都被更换。修复后的修复体在咬合过程中引起下颌骨的侧向位移，因此导致侧向而不是轴向过度咬合负荷。保持修复体的种植体每周刷1次，龈下清洁每月1次。其余植入物从未清洁，此外，在每个植入物周围被动放置棉绳以促进斑块积聚。咬合负荷过大的8个种植体中有5个失去了骨整合（活动性和种植体周围射线可透性）。在咬合负荷开始后4.5个月至15.5个月观察到骨整合的丧失。尽管在18个月后评估的影像学骨水平平均损失1.8 mm，但没有一个有斑块积聚的种植体失去骨结合。(C)Munksgaard，1996年。
The breakdown of bone around oral implants following excessive occlusal load or plaque accumulation was evaluated in monkeys. 5 screw type implants of pure titanium (Astra) were inserted in the mandible of 4 monkeys (Macaca Fascicularis). 2 implants were placed in each of the lateral segments and 1 in the frontal area. Each monkey was provided with 2 cemented splints covering the premolars and molars in the right and left side of the maxilla, respectively. 6 months after insertion of the fixtures, a fixed partial prosthesis was mounted on the 2 implants in one of the lateral segments. The prosthesis was in supra-occlusal contact with the antagonizing splint. Each prosthesis was replaced during the course of the experiment. The renewed prosthesis caused a lateral displacement of the mandible during occlusion, and therefore resulted in a lateral rather than axial excessive occlusal load. Implants retaining the prosthesis were brushed 1 x a week and subgingival cleaning was performed 1 x a month. The remaining implants were never cleaned and, additionally, a cotton cord was placed passively around each of these to promote plaque accumulation. 5 out of 8 implants with excessive occlusal load lost osseointegration (mobility and peri-implant radiolucency). The loss of osseointegration was observed 4.5 months to 15.5 months after the occlusal overload was commenced. None of the implants with plaque accumulation lost osseointegration, although an average loss of 1.8 mm in the radiographic bone level was assessed after 18 months. (C) Munksgaard, 1996.