CLINICAL EVALUATION OF A RECOMBINANT HEPATITIS B VACCINE
CLINICAL EVALUATION OF A RECOMBINANT HEPATITIS B VACCINE
复制标题
重组乙型肝炎疫苗的临床评价
DOI：
10.1016/s0140-6736(84)92740-5
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发表时间：
1984
期刊：
影响因子：
--
通讯作者：
F. Deinhardt
中科院分区：
文献类型：
--
作者：
W. Jilg;M. Schmidt;G. Zoulek;B. Lorbeer;B. Wilske;F. Deinhardt
2 patients had neurological symptoms and signs, with evidence of central-nervous-system demyelination, 6 weeks after administration of recombinant hepatitis B vaccine. 1 had known multiple sclerosis but the other had no history of neurological disease; both had HLA haplotypes DR2 and B7, which are associated with multiple sclerosis. A causal link between vaccination and demyelination cannot be established from these 2 case-reports, but the time interval would fit a proposed immunological mechanism.
影响因子：
29.4
作者：
H. Satoh;P. Guth;M. Grossman
通讯作者：
H. Satoh;P. Guth;M. Grossman